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Is there a genetic risk for thiopurine-induced hair loss?
Although this study was a retrospective single-center case-control observational study that enrolled a small number of patients, NUDT15 R139C homozygosity is a genetic risk of thiopurine-induced potentially fetal hematological abnormalities.
Where to take azathioprine for inflammatory bowel disease?
In terms of disease distribution, some studies have demonstrated colonic distribution of CD to be significant in favouring remission with azathioprine, while others have not.1,2, 7–8 In the UK, most IBD is managed in district general hospitals, with complex cases being referred to tertiary teaching hospitals.
How is AZA related to leukocytopenia and hair loss?
Azathioprine (AZA)-metabolizing enzyme gene polymorphism is strongly related to thiopurine-induced leukocytopenia, which has not been well recognized in dermatological practice.
Last Update: Oct 2021